Spuyten Duyvil station is a commuter rail stop on the Metro-North Railroad's Hudson Line, serving the Spuyten Duyvil neighborhood of the Bronx, New York City.

On the evening of January 13, 1882, a southbound New York Central passenger train crashed into the rear of another one stopped on the tracks along Spuyten Duyvil Creek in the similarly-named neighborhood of the New York City borough of The Bronx. Eight people were killed, and 19 seriously injured, by the crash and fires afterwards, fires that neighborhood residents and crew extinguished by rolling large snowballs into them until local firefighters arrived. Among the dead was State Senator Webster Wagner, inventor of the sleeping cars used on the train, between two of which he was crushed to death, and a newlywed couple who died together after the bride refused to allow a rescuer to cut her clothing so she could escape. It was the deadliest rail accident in New York City at that time, remaining so for another 20 years.