Squidbillies is an American adult animated sitcom created by Jim Fortier and Dave Willis for Cartoon Network's late night programming block Adult Swim. An unofficial pilot for the series aired on April 1, 2005. The series later made its official debut on October 16, 2005 and ended on December 12, 2021, with a total of 132 episodes over the course of 13 seasons.

Adult Swim is an American programming block broadcast by the American basic cable channel Cartoon Network during the evening, prime time, and late-night dayparts. The block features stylistically varied animated and live-action series targeting an adult audience. The content includes original programming, syndicated series, and short films with generally minimal or no editing for content. Adult Swim is programmed by Williams Street, a subsidiary of Warner Bros. Television Studios that also produces much of the block's original programming.