St. Elsewhere is the debut album by American soul duo Gnarls Barkley. It was released on April 24, 2006, in the United Kingdom, where it debuted at number one on the UK Albums Chart, and on May 9, 2006, in the United States, although it was available for purchase one week earlier as a digital download in the US iTunes Store. St. Elsewhere debuted at No. 20 on the US Billboard 200, and peaked at No. 4. It topped the Billboard Dance/Electronic Albums chart for 39 non-consecutive weeks in 2006 and 2007.

Gnarls Barkley is an American soul duo composed of singer-songwriter CeeLo Green and producer Danger Mouse. They released their debut studio album, St. Elsewhere, in 2006. It contained their hit single "Crazy", which peaked at number two on the US Hot 100 and topped the UK Singles Chart. It was nominated at the 2007 Grammy Awards for Record of the Year, and was platinum certified for shipping over 1,000,000 records. St. Elsewhere also received a nomination for Album of the Year. The Odd Couple, their second studio album, was scheduled for release in April 2008, but due to a leak of the album over the internet, they decided to release it early. The album in its entirety received similarly positive reviews.