The St. Frances Xavier Cabrini Shrine is located at 701 Fort Washington Avenue between Fort Tryon Park and West 190th Street, with a facade on Cabrini Boulevard, in the Hudson Heights neighborhood of Washington Heights in Upper Manhattan, New York City. It is dedicated to Saint Frances Xavier Cabrini, who in 1946 became the first American citizen to be canonized by the Roman Catholic Church.

Hudson Heights is a residential neighborhood within Washington Heights in Upper Manhattan, New York City. Most residences are apartment buildings, many of which are cooperatives, and most were constructed in the 1920s through 1940s. The Art Deco style is prominent, along with Tudor Revival. Notable complexes include Hudson View Gardens and Castle Village, which were both developed by Dr. Charles V. Paterno, and were designed by George F. Pelham and his son, George F. Pelham, Jr., respectively.