St. James' Church is a former collegiate church in Antwerp, Belgium. The church is built on the site of a hostel for pilgrims to Santiago de Compostela. The present building is the work of the Waghemakere family and Rombout Keldermans, in Brabantine Gothic style. The church contains the grave of Peter Paul Rubens in the eastern chapel.

In Christianity, a collegiate church is a church where the daily office of worship is maintained by a college of canons, a non-monastic or "secular" community of clergy, organised as a self-governing corporate body, headed by a dignitary bearing a title which may vary, such as dean or provost.