St. James or Saint James is a town in Brunswick County, North Carolina, United States. The population was 3,165 at the 2010 census, up from 804 in 2000. It is part of the Wilmington, NC Metropolitan Statistical Area.

Brunswick County is a county located in the U.S. state of North Carolina. It is the southernmost county in the state. As of the 2020 census, the population was 136,693. Its population was only 73,143 in 2000, making it one of the fastest-growing counties in the state. With a nominal growth rate of approximately 47% in ten years, much of the growth is centered in the eastern section of the county in the suburbs of Wilmington such as Leland, Belville and Southport. The county seat is Bolivia, which at a population of around 150 people is among the least populous county seats in the state.