St. John Vianney High School is a Marianist private, all-boys Catholic college preparatory school in Kirkwood, Missouri. The school was opened in 1960 by the Society of Mary, a religious order of priests and brothers who continue to run the school, and is part of the Archdiocese of Saint Louis, along with the Marianists' Chaminade College Preparatory School and St. Mary's High School.

Kirkwood is an inner-ring western suburb of St. Louis located in St. Louis County, Missouri. As of the 2010 census, the city's population was 27,540. Founded in 1853, the city is named after James P. Kirkwood, builder of the Pacific Railroad through that city. It was the first planned suburb located west of the Mississippi River.