St. Paul's Co-educational College, is an Anglican secondary school located at 33 MacDonnell Road, Mid-Levels, Hong Kong. Founded in 1915, it was a girls-only college until after World War II. The college offers the HKDSE and IBDP curricula in parallel. It is the first Round Square school in greater China. Since 2001, it has been under the Direct Subsidy Scheme. It has an affiliated primary school, making it a school of the "through-train" system.

MacDonnell Road is a street in the Mid-Levels area of Hong Kong Island, Hong Kong.