St. Paul Island is a small uninhabited island located approximately 24 km (15 mi) northeast of Cape North on Cape Breton Island and 71 km (44 mi) southwest of Cape Ray on Newfoundland; it is along the boundary between the Gulf of St. Lawrence and the Cabot Strait.

The Gulf of St. Lawrence fringes the shores of the provinces of Quebec, New Brunswick, Nova Scotia, Prince Edward Island, Newfoundland and Labrador, in Canada, plus the islands Saint-Pierre and Miquelon, possessions of France, in North America.