St. Philomena's Cathedral is a Catholic church that is the cathedral of the Diocese of Mysore, India. The full name is the Cathedral of St. Joseph and St. Philomena. It is also known as St. Joseph's Cathedral. It was constructed in 1936 using a Neo Gothic style and its architecture was inspired by the Cologne Cathedral in Germany. This is one of the tallest churches in Asia.

The Roman Catholic Diocese of Mysore is a suffragan Latin diocese, in the ecclesiastical province of Bangalore in southern India, yet depends on the missionary Dicastery for Evangelization. Its cathedral episcopal see is St. Philomena's Cathedral in the city of Mysore in Karnataka.