Saint Rose is a census-designated place (CDP) in St. Charles Parish, Louisiana, United States. St. Rose is on the east bank of the Mississippi River, two miles (3 km) north of the Jefferson Parish border and is part of the Greater New Orleans metropolitan area. The population was 6,540 in the 2000 census, and 7,504 in 2020.

St. Charles Parish is a parish located in the U.S. state of Louisiana. At the 2020 census, its population was 52,549. The parish seat is Hahnville and the most populous community is Luling.