St Ann's Church is a Church of England parish church in Manchester, England. Although named after St Anne, it also pays tribute to the patron of the church, Ann, Lady Bland. St Ann's Church is a Grade I listed building.

There are 48 Grade I listed buildings in Greater Manchester, England. In the United Kingdom, the term listed building refers to a building or other structure officially designated as being of special architectural, historical or cultural significance; Grade I structures are those considered to be "buildings of exceptional interest". In England, the authority for listing under the Planning Act 1990 rests with Historic England, a non-departmental public body sponsored by the Department for Culture, Media and Sport.