St Mary's Church is a Church of England parish church in Chaddesden, a suburb of Derby, England. One of the oldest churches in the city, it is a Grade I listed building dating back to the mid-14th century.

Chaddesden, also known locally as Chadd, is a large residential suburb of Derby, in the ceremonial county of Derbyshire, England. Historically a separate village centred on Chaddesden Hall and the 14th century St Mary's Church, the area was significantly expanded by 20th-century housing developments, and became part of the then County Borough of Derby in 1968, prior to Derby's city status in 1977.