The Stade Region emerged in 1823 by an administrative reorganisation of the dominions of the Kingdom of Hanover, a sovereign state, whose then territory is almost completely part of today's German federal state of Lower Saxony. Until 1837 the Kingdom of Hanover was ruled in personal union by the Kings of the United Kingdom of Great Britain and Ireland.

The Kingdom of Hanover was established in October 1814 by the Congress of Vienna, with the restoration of George III to his Hanoverian territories after the Napoleonic era. It succeeded the former Electorate of Hanover, and joined 38 other sovereign states in the German Confederation in June 1815. The kingdom was ruled by the House of Hanover, a cadet branch of the House of Welf, in personal union with Great Britain between 1714 and 1837. Since its monarch resided in London, a viceroy, usually a younger member of the British royal family, handled the administration of the Kingdom of Hanover.