Amos Alonzo Stagg Field is the name of two successive football fields for the University of Chicago. Beyond sports, the first Stagg Field (1893–1957), named for famed coach, Alonzo Stagg, is remembered for its role in a landmark scientific achievement of Enrico Fermi and the Metallurgical Laboratory during the Manhattan Project. The site of the first artificial nuclear chain reaction, which occurred within the field's west viewing-stands structure, received designation as a National Historic Landmark on February 18, 1965. On October 15, 1966, which is the day that the National Historic Preservation Act of 1966 was enacted creating the National Register of Historic Places, it was added to that as well. The site was named a Chicago Landmark on October 27, 1971.

The Joseph Regenstein Library, often referred to by students as "The Reg", is the main library of the University of Chicago, named after the industrialist and philanthropist Joseph Regenstein. It is one of the largest repositories of books in the world and is noted for its brutalist architecture.