Stanton Street Synagogue, also known as Stanton Street Shul and Congregation Bnai Jacob Anshei Brzezan, is an Orthodox Jewish synagogue located at 180 Stanton Street on the Lower East Side of Manhattan, in New York City, New York, United States.

Stanton Street is a west-to-east street in the New York City borough of Manhattan, in the neighborhood of the Lower East Side. The street begins at the Bowery in the west and runs east to a dead end past Pitt Street, adjacent to Hamilton Fish Park. A shorter section of Stanton Street also exists east of Columbia Street; it was isolated from the remainder of the street in 1959 with the construction of the Gompers Houses and the Masaryk Towers.