Massachusetts Route 71 and New York State Route 71 (NY 71) are adjoining state highways in the states of Massachusetts and New York in the United States. The two highways form a continuous roadway connecting NY 22 in Hillsdale, Columbia County, New York, to Route 23 and Route 41 in Great Barrington, Berkshire County, Massachusetts. Combined, Route 71 and NY 71 extend for 7.93 miles (12.76 km) as a two-lane road through mostly rural areas in the Taconic Mountains, serving only small, unincorporated communities in both states. Both routes are part of the Henry Knox Trail.

New York State Route 22 (NY 22) is a north–south state highway that parallels the eastern border of the U.S. state of New York, from the outskirts of New York City to the hamlet of Mooers in Clinton County near the Canadian border. At 337 miles (542 km), it is the state's longest north–south route and the third longest state route overall, after NY 5 and NY 17. Many of the state's major east–west roads intersect with, and often join, NY 22 just before crossing into the neighboring New England states, where U.S. Route 7 (US 7), which originally partially followed NY 22's alignment, similarly parallels the New York state line.