Ste. Anne, or Sainte-Anne-des-Chênes, is a town in Manitoba, Canada, located about 42 km southeast of Winnipeg. The population was 2,114 in 2016, 1,524 in 2011, and 1,513 in 2011. It is known for being located on the Seine River and at the heart of the Old Dawson Trail. The town is surrounded by the Rural Municipality of Ste. Anne.

Provincial Trunk Highway 12 is a provincial primary highway located in the Canadian province of Manitoba. Lying entirely in the Eastman Region, it runs from the U.S. border to a dead end in Grand Beach. PTH 12 forms the Manitoba section of MOM's Way, a tourist route from Thunder Bay to Winnipeg. PTH 12 is primarily a two-lane highway except for two four-lane stretch between Steinbach and PTH 1 and a ten-kilometre concurrency with PTH 44.