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Steely Dan

Steely Dan is an American rock duo founded in 1972 by core members Walter Becker and Donald Fagen. Blending rock, latin music, traditional pop, R&B, sophisticated studio production with cryptic and ironic lyrics, the band enjoyed critical and commercial success starting from the early 1970s until breaking up in 1981. Throughout their career, the duo recorded with a revolving cast of session musicians, in 1974 retired from live performances to become a studio-only band. Rolling Stone has called them "the perfect musical antiheroes for the Seventies". After the group disbanded in 1981, Becker and Fagen were less active throughout most of the next decade, though a cult following remained devoted to the group. Since reuniting in 1993, Steely Dan has toured and released two albums of new material, the first of which, Two Against Nature, earned a Grammy Award for Album of the Year, they have sold more than 40 million albums worldwide and were inducted into the Rock and Roll Hall of Fame in March 2001.

VH1 ranked Steely Dan at #82 on their list of the 100 greatest musical artists of all time. Founding member Walter Becker died on September 2017, leaving Fagen as the sole official member. Becker and Fagen met in 1967 in Annandale-on-Hudson, New York; as Fagen passed by a café, The Red Balloon, he heard Becker practicing the electric guitar. In an interview, Fagen recounted the experience: "I hear this guy practicing, it sounded professional and contemporary, it sounded like, you know, like a black person, really." He introduced himself to Becker and asked, "Do you want to be in a band?" Discovering that they enjoyed similar music, the two began writing songs together. Becker and Fagen began playing in local groups. One such group, known as the Don Fagen Jazz Trio, the Bad Rock Group and the Leather Canary, included future comedy star Chevy Chase on drums, they played covers of songs by The Rolling Stones, Moby Grape, Willie Dixon, as well as some original compositions. Terence Boylan, another Bard musician, remembered that Fagen took to the beatnik life while attending college: "They never came out of their room, they stayed up all night.

They looked like ghosts -- black turtlenecks and skin so white. No activity, chain-smoking Lucky Strikes and dope." Fagen himself would remember it as "probably the only time in my life that I had friends."After Fagen graduated in 1969, the two moved to Brooklyn and tried to peddle their tunes in the Brill Building in midtown Manhattan. Kenny Vance, who had a production office in the building, took an interest in their music, which led to work on the soundtrack of the low-budget Richard Pryor film You've Got to Walk It Like You Talk It or You'll Lose That Beat. Becker said bluntly, "We did it for the money." A series of demos from 1968 to 1971 are available in multiple different releases, not authorized by Becker and Fagen. This collection features 25 tracks and is notable for its sparse arrangements and lo-fi production, a contrast with Steely Dan's work. Although some of these songs were re-recorded for Steely Dan albums, most were never released. Becker and Fagen joined the touring band of Jay and the Americans for a half.

They were at first paid $100 per show, but partway through their tenure the band's tour manager cut their salaries in half. The group's lead singer, Jay Black, dubbed Becker and Fagen "the Manson and Starkweather of rock'n' roll", referring to cult leader Charles Manson and spree killer Charles Starkweather, they had little success after moving to Brooklyn, although Barbra Streisand recorded their song "I Mean To Shine" on her 1971 Barbra Joan Streisand album. Their fortunes changed when one of Vance's associates, Gary Katz, moved to Los Angeles to become a staff producer for ABC Records, he hired Fagen as staff songwriters. Katz would produce all their 1970s albums in collaboration with engineer Roger Nichols. Nichols would win six Grammy Awards for his work with the band from the 1970s to 2001. After realizing that their songs were too complex for other ABC artists, at Katz's suggestion Becker and Fagen formed their own band with guitarists Denny Dias and Jeff "Skunk" Baxter, drummer Jim Hodder and singer David Palmer, Katz signed them to ABC as recording artists.

Fans of Beat Generation literature and Becker named the band after a "revolutionary" steam-powered dildo mentioned in the William S. Burroughs novel Naked Lunch. Palmer joined as a second lead vocalist because of Fagen's occasional stage fright, his reluctance to sing in front of an audience, because the label believed that his voice was not "commercial" enough. In 1972, ABC issued Steely Dan's first single, "Dallas", backed with "Sail the Waterway". Distribution of "stock" copies available to the general public was extremely limited; as of 2015, "Dallas" and "Sail the Waterway" are the only released Steely Dan tracks that have not been reissued on cassette or compact disc. In an interview and Fagen called the songs "stinko." "Dallas" was covered by Poco on their Head Over Heels album. Can't Buy a Thrill, Steely Dan's debut album, was released in 1972, its hit singles "Do It Again" and "Reelin' In the Years" reached No. 6 and No. 11 on the Billboard singles chart. Along with "Dirty Work", the songs became staples on classic


C2C12 is an immortalized mouse myoblast cell line. The C2C12 cell line is a subclone of myoblasts that were obtained by Yaffe and Saxel at the Weizmann Institute of Science in Israel in 1977. Developed for in vitro studies of myoblasts isolated from the complex interactions of in vivo conditions, C2C12 cells are useful in biomedical research; these cells are capable of rapid proliferation under high serum conditions and differentiation into myoblasts under low serum conditions. Mononucleated myoblasts can fuse to form multinucleated myotubes under low serum conditions or starvation, leading to the precursors of contractile skeletal muscle cells in the process of myogenesis. C2C12 cells are used to study the differentiation of myoblasts and myogenesis, to express various target proteins, to explore mechanistic biochemical pathways. Wild-type C2C12 cells have a radial branching morphology consisting of long fibers extending in many directions. C2C12 cells can be cultured in a variety of conditions to induce specific responses of interest.

For example, assisted by the cell line's high differentiation rate and fusion rate, fibronectin templates can be micro-plated to petri dishes or cell culture flasks in order to induce specific growth patterns, such as that of skeletal muscle cell interactions with extracellular matrix components. The introduction of adhesion molecules can alter the growth pattern of C2C12 cells to a longitudinal distribution exhibiting polarity. There are many ways to regulate the shape of C2C12 myoblasts genetically and environmentally, from stress, to cytoskeleton alteration, to growth factors; the scaffolding of C2C12 cells is important for studying muscle tissue regeneration post-injury or after tissue wasting due to disease or ICU rehabilitation. C2C12 cells have been shown to incorporate exogenous cDNA and nucleic acids by transfection. In the piloting research conducted by Yaffe and Saxel, C2C12 were obtained through serial passage of myoblasts cultured from the thigh muscle of C3H mice after crush injury.

In their study, a set of C2C12 cells were cultured from mice homozygous recessive for the dy gene. These mice exhibited a syndrome similar to early-onset human muscular dystrophy. Normal mouse myoblasts were cultured from 2-month old C3H mice after crush injury. Within two days, the normal cells differentiated into spindle-shaped mononucleated myoblasts. After four days, multinucleated myotube networks formed, a few days after, sarcomeres and Z-lines could be observed. In contrast, the dystrophic cells formed shortened fibers covered in fibroblasts, a hallmark of muscle wasting. C2C12 cells demonstrate rapid development and maturation into functional skeletal muscle cells or cardiac muscle cells, having the ability to contract and generate force; the rate of muscle formation from C2C12 cells can be controlled by the introduction of loss-of-functions genes vital for the fusion of myoblasts and myogenesis. Under necrotic conditions, such as tumor necrosis factor alpha, direct protein loss myosin heavy chain protein, in C2C12 skeletal muscle cells has been shown.

C2C12 cells were used to elucidate inactivated X chromosome replication during early S-phase of the cell cycle and is regulated epigenetically. C2C12 cells are convenient for studying the cell cycle due to its high division rate. Cellosaurus entry for C2C12

(148209) 2000 CR105

2000 CR105 is a trans-Neptunian object and the tenth-most-distant known object in the Solar System as of 2015. Considered a detached object, it orbits the Sun in a eccentric orbit every 3305 years at an average distance of 222 astronomical units. Mike Brown's website lists it as a possible dwarf planet with a diameter of 328 kilometres based on an assumed albedo of 0.04. The albedo is expected to be low. However, if the albedo is higher, the object could be half that size. 2000 CR105 and Sedna differ from scattered-disc objects in that they are not within the gravitational influence of the planet Neptune at their perihelion distances. It is something of a mystery as to how these objects came to be in their far-flung orbits. Several hypotheses have been put forward: They were pulled from their original positions by a passing star, they were pulled from their original positions by a distant, as-yet-undiscovered, giant planet. They were pulled from their original positions by an undiscovered companion star orbiting the Sun such as Nemesis.

They were captured from another planetary system during a close encounter early in the Sun's history. According to Kenyon and Bromley, there is a 15% probability that a star like the Sun had an early close encounter and a 1% probability that outer planetary exchanges would have happened. 2000 CR105 is estimated to be 2–3 times more to be a captured planetary object than Sedna. 2000 CR105 is the first object discovered in the Solar System to have a semi-major axis exceeding 150 AU, a perihelion beyond Neptune, an argument of perihelion of 340 ± 55°. It is one of eleven objects known with a semi-major axis greater than 100 AU and perihelion beyond 42 AU, it may be influenced by Planet Nine. 2004 VN112 2000 OO67 Clearing the neighbourhood Planets beyond Neptune List of Solar System objects most distant from the Sun in 2015 List of Solar System objects by greatest aphelion Orbit Determination of 2000 CR105 Spacecraft escaping the Solar System World Book: Worlds Beyond Pluto 2000 CR105 at AstDyS-2, Asteroids—Dynamic Site Ephemeris · Observation prediction · Orbital info · Proper elements · Observational info 2000 CR105 at the JPL Small-Body Database Close approach · Discovery · Ephemeris · Orbit diagram · Orbital elements · Physical parameters

John Doulton

John Doulton was an English businessman and manufacturer of pottery, a founder of the firm that became known as Royal Doulton. John Doulton married Jane Duneau, a widow from Bridgnorth in Shropshire, who died on 9 April 1841, they had eight children, including Sir Henry, MP Frederick and Alfred. In 1815, soon after John Doulton had completed his apprenticeship as a potter, he invested his life savings of £100 in the Vauxhall Walk pottery of Martha Jones, Lambeth, her foreman, John Watts, was taken into partnership and the firm became known as Jones and Doulton. It specialized in industrial ware, brown stoneware, drain pipes as well as stoneware bottles for chemicals and other industrial liquids among others. Martha Jones withdrew from the partnership in 1820 and the company moved to new premises in Lambeth High Street in 1826. In 1835 John's 15-year-old son Henry Doulton was taken on as an apprentice. By 1846, Henry had set up an independent Lambeth Pottery which had become the leader in industrial products sanitation products.

Following the retirement of John Watts in 1853, Doulton and Watts merged with Henry's company to become Doulton and Company and was recognised for its lines of hand decorated figurines and dinnerware. Eyles, D. Royal Doulton, 1815–1965: The Rise and Expansion of the Royal Doulton Potteries, London: Hutchinson Eyles, D.. The Doulton Lambeth wares, London: Richard Dennis, ISBN 0-903685-79-5 Eyles, D.. Royal Doulton Figures: Produced at Burslem, Staffordshire, c1890-1994, London: Richard Dennis, ISBN 0-903685-35-3

Sun Qingmei

Sun Qingmei is a Chinese former footballer who played for the China national team at the 1991 and 1995 editions of the FIFA Women's World Cup and won a silver medal at the 1996 Atlanta Olympics. During her childhood in Hebei, Sun's parents locked her in her bedroom in a bid to stop her playing football, she was a member of the state track and field team when she started football training in 1983 and joined the Hebei club in 1984. After the 1991 Women's World Cup, Sun accepted a transfer to the Japan Women's Football League with Matsushita Denki, she helped. At the 1988 FIFA Women's Invitation Tournament in Guangdong she was part of the hosts' team who lost the third place play-off to Brazil; the Chinese press voted her into the tournament's official all-star team. At the 1991 FIFA Women's World Cup, Sun played the full 80 minutes in all four of China's games; the hosts reached the quarter-finals before losing 1–0 to Sweden. In the first FIFA Women's World Cup match, Sun scored the fourth goal in China's 4–0 win over eventual finalists Norway on 16 November 1991.

In 1996 Sun won the Olympic silver medal with the Chinese team. She played all five scored three goals, she retired from football after helping China retain the AFC Women's Asian Cup at the 1997 AFC Women's Championship in December 1997. Sun Qingmei – FIFA competition record Profile

Marpesia (butterfly)

Marpesia is a butterfly genus in the family Nymphalidae. The species of this genus are found in the Nearctic realms; the genus includes the following species, listed alphabetically: Marpesia berania – amber daggerwing Marpesia chiron – many-banded daggerwing Marpesia corinna – Corinna daggerwing Marpesia corita – orange-banded daggerwing Marpesia crethon – Crethon daggerwing Marpesia egina – Egina daggerwing Marpesia eleuchea Hübner, 1818 – Antillean daggerwing Marpesia furcula – sunset daggerwing Marpesia harmonia – pale daggerwing or Harmonia daggerwing Marpesia livius – Livius daggerwing Marpesia marcella – pansy daggerwing Marpesia merops – dappled daggerwing Marpesia orsilochusOrsilochus daggerwing Marpesia petreus – ruddy daggerwing Marpesia themistocles – Norica daggerwing Marpesia tutelina – Tutelina daggerwing Marpesia zerynthia Hübner, – waiter daggerwing