Stephen King's Desperation is a 2006 American made-for-TV horror film based on Stephen King's 1996 novel of the same name. King himself wrote the teleplay. The film was directed by frequent King collaborator Mick Garris and stars Ron Perlman, Tom Skerritt, Steven Weber and Annabeth Gish.

Desperation is a horror novel by American author Stephen King. It was published in 1996 at the same time as its "mirror" novel, The Regulators, itself published under King's Richard Bachman pseudonym. It was also made into a TV film starring Ron Perlman, Tom Skerritt and Steven Weber in 2006. The two novels represent parallel universes relative to one another, and most of the characters present in one novel's world also exist in the other novel's reality, albeit in different circumstances.