"Stewie Goes for a Drive" is the fourth episode of the tenth season of the animated comedy series Family Guy, and the 169th episode overall. It originally aired on Fox in the United States on November 6, 2011. The plot depicts actor Ryan Reynolds moving into the house across the street, and Peter Griffin befriending him. Ryan flirts with Peter, making Peter uncomfortable, and their friendship ends. Meanwhile, Stewie takes Brian's car for a joy ride, and crashes it into a lamp post. Fearing the consequences, Stewie runs away from home, but then needs Brian's help when he ends up in a bad part of town.

The tenth season of Family Guy premiered on the Fox network from September 25, 2011, to May 20, 2012 with a one-hour broadcast of two episodes. The series follows the Griffin family, a dysfunctional family consisting of father Peter, mother Lois, daughter Meg, son Chris, baby Stewie and the family dog Brian, who reside in their hometown of Quahog, a fictional city in Rhode Island.