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Ivan Pavlov
Ivan Pavlov
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A dose response curve showing the normalised tissue response to stimulation by an agonist. Low doses are insufficient to generate a response, while hi
A dose response curve showing the normalised tissue response to stimulation by an agonist. Low doses are insufficient to generate a response, while high doses generate a maximal response. The steepest point of the curve corresponds with an EC50 of 0.7 molar
Semi-log plots of the hypothetical response to agonist, log concentration on the x-axis, in combination with different antagonist concentrations. The
Semi-log plots of the hypothetical response to agonist, log concentration on the x-axis, in combination with different antagonist concentrations. The parameters of the curves, and how the antagonist changes them, gives useful information about the agonist's pharmacological profile. This curve is similar but distinct from that, which is generated with the ligand-bound receptor concentration on the y-axis.