The Stockport–Stalybridge line is a railway line in Greater Manchester, England, running north-east from Stockport to Stalybridge, via Guide Bridge. The line is used mainly by freight and empty stock workings, although it once had a frequent passenger service. In 1992, the service pattern reduced to a single weekly passenger train but, in 2018, this was increased to twice a week: one service in each direction on Saturday mornings. Services are operated by Northern, usually with a Class 150 diesel multiple unit. The line is intended to be electrified as part of the Transpennine Route Upgrade.

Stockport railway station serves the large town of Stockport in Greater Manchester, England. It is located 6 miles south-east of Manchester Piccadilly, on a spur of the West Coast Main Line to London Euston.