Strasburg is a borough in Lancaster County, Pennsylvania, United States. It developed as a linear village stretching approximately 2 miles (3 km) along the Great Conestoga Road, later known as the Strasburg Road. The population was 3,117 at the 2020 census.

Strasburg Road was an early road in Pennsylvania connecting Philadelphia to Strasburg in Lancaster County. The route was surveyed by John Sellers and others in 1772-3 under the colonial administration of Governor Richard Penn and completed under the new administration of the independent state of Pennsylvania. The route started at the "second ferry" on the Schuylkill River, today's Market Street in Philadelphia, and went through West Chester, East Fallowfield Township, and Gap, before ending in Strasburg. Earlier roads travelled much the same route, including a Native American path in use as early as 1620.