Sudlersville is a town in the far northeastern corner of Queen Anne's County, Maryland, United States. The ZIP code is 21668 and the area code is 410. The population was 497 at the 2010 census. It is perhaps best known as the hometown of Baseball Hall Of Fame slugger Jimmie Foxx. Other famous residents include astronomer and mathematician Simon Newcomb.

Queen Anne's County is located on the Eastern Shore of the U.S. state of Maryland. As of the 2020 census, the population was 49,874. Its county seat and most populous municipality is Centreville. The census-designated place of Stevensville is the county's most populous place with population of 7,442 as of 2020. The county is named for Queen Anne of Great Britain, who reigned when the county was established in 1706 during the colonial period.