The Sultanah Aminah Hospital is one of the oldest historical government-funded multi-specialty hospital since 1882, it located in Johor Bahru, Johor, Malaysia. It is the largest hospital in Johor and the main referral and tertiary health centre for the state. HSA is also one of the busiest hospitals in Malaysia based on patient load. However, budget cuts have affected its level of service.

Sultan Sir Ismail Al-Khalidi Ibni Almarhum Sultan Sir Ibrahim Al-Masyhur was the 23rd Sultan of Johor and the 3rd Sultan of Modern Johor.