The Symphony in E minor is the first symphony written by the American composer Florence Price. The work was completed in 1932 and was first performed by the Chicago Symphony Orchestra under the conductor Frederick Stock in June 1933. The piece was Price's first full-scale orchestral composition and was the first symphony by a Black woman to be performed by a major American orchestra.

Florence Beatrice Price was an American classical composer, pianist, organist and music teacher. Born in Little Rock, Arkansas, Price was educated at the New England Conservatory of Music, and was active in Chicago from 1927 until her death in 1953. Price is noted as the first African-American woman to be recognized as a symphonic composer, and the first to have a composition played by a major orchestra. Price composed over 300 works: four symphonies, four concertos, as well as choral works, art songs, chamber music and music for solo instruments. In 2009, a substantial collection of her works and papers was found in her abandoned summer home.