The TVB Anniversary Award for Most Popular Female Character is one of the TVB Anniversary Awards presented annually by Television Broadcasts Limited (TVB) to recognize an actress who has delivered a popular performance in a Hong Kong television drama role throughout the designated year. The My Favourite Female Television Role (我最喜愛的電視女角色) was not introduced to the awards ceremony until 2006, nine years after its establishment. In 2013, the name was changed to Most Popular Female Television Role (最受歡迎電視女角色).

Charmaine Sheh Sze-man is a Hongkonger actress and beauty pageant titleholder who placed second runner-up at Miss Hong Kong pageant 1997 and represented her country at Miss International 1997. Sheh signed a contract with TVB in 1998. She is best known for her roles in Return of the Cuckoo (2000), War and Beauty (2004), Maidens' Vow (2006), Forensic Heroes II (2008), Beyond the Realm of Conscience (2009), Can't Buy Me Love (2010), When Heaven Burns (2011), Line Walker (2014), Story of Yanxi Palace (2018) and The QUEEN of News (2023).