Takezaki Suenaga was a retainer of the Higo Province, Japan who fought in both the Battle of Bun'ei and the Battle of Kōan during the Mongol invasions of Japan. Suenaga commissioned the Mōko Shūrai Ekotoba, a pictorial scroll showing his own valor in war, composed in 1293. During the Mongol invasion of 1274, Suenaga fought at Hakata under Muto Kagesuke. Suenaga sold his horses and saddles to pay for a trip to Kamakura to report his deeds in battle to the bakufu. To receive rewards for valorous deeds from the bakufu, others had to witness the deeds and report them directly to the bakufu. By his own account in the scrolls, Suenaga says, “Other than advancing and having my deeds known, I have nothing else to live for,” showing that, first, he wanted to advance in terms of measurable money and rank, that, just as he sought fame and recognition. Suenaga goes to great lengths to achieve. Although he is under orders from Kagesuke, the commander, to pull back at the beginning, Suenaga disobeys. Asserting his own identity, he says, “Waiting for the general will cause us to be late to battle.

Of all the warriors of the clan, I, Suenaga will be the first to fight from Higo.” Rushing forward on his own, Suenaga encounters Kagesuke himself. Again Suenaga disobeys this time from Kagesuke's retainer; when he is ordered to dismount from his horse, he refuses, citing his desire to be the first into battle. Mongol Invasion Scrolls Online interactive viewer for Moko Shurai Ekotoba from Bowdoin College. Takezaki Suenaga Samurai-archives.com Mōko Shūrai Ekotoba Battle of Bun'ei Battle of Kōan Mongol Invasions of Japan Genko Borui

Injectable filler is a soft tissue filler injected into the skin at different depths to help fill in facial wrinkles, provide facial volume, augment facial features: restoring a smoother appearance. Most of these wrinkle fillers are temporary because they are absorbed by the body; some people may need more than one injection to achieve the wrinkle-smoothing effect. The effect lasts for about six months or longer. Successful results depend on health of the skin, skill of the health care provider, type of filler used. In the US, fillers are approved as medical devices by the Food and Drug Administration and the injection is prescribed and performed by a health care provider. Fillers are not approved for certain parts of the body where they can be unsafe, including the penis. In Europe and the UK, fillers are non-prescription medical devices that can be injected by anyone licensed to do so by the respective medical authorities, they require a CE mark, which regulates adherence to production standards, but does not require any demonstration of medical efficacy.

As a result, there are over 140 injectable fillers in the UK/European market and only six approved for use in the US. Dermal fillers known as "injectables" or "soft-tissue fillers," do just what their name suggests: they fill in the area under the skin. Treating fat loss secondary to HIV. Fillers were found to give a temporary acceptable therapeutic effect in HIV‐infected patients with severe facial lipodystrophy, caused by the active antiretroviral therapy. A systemic review concluded that the injectable fillers resulted in high satisfaction, further research is needed to determine the safety of its use. Risks of an improperly performed dermal filler procedure include bruising, pain or itching. Less there may be infections or allergic reactions, which may cause scarring and lumps that may require surgical correction. More serious adverse effects such as blindness due to retrograde embolization into the ophthalmic and retinal arteries can occur. Delayed skin necrosis can occur as a complication of embolization.

Embolic complications are more seen when autologous fat is used as a filler, followed by hyaluronic acid. Though rare, when vision loss does occur, it is permanent. Fillers are made of sugar molecules or composed of hyaluronic acids, collagens — which may come from pigs, cadavers, or may be generated in a laboratory — the person's own transplanted fat, biosynthetic polymers. Examples of the latter include calcium hydroxylapatite, polymethylmethacrylate, polylactic acid. In 2012, "Artiste Assisted Injection System" was launched in the US market to assist in the delivery of dermal fillers. A study concluded that the injecting device can achieve reductions in patient discomfort and adverse events by controlling the rate of flow of injection of the filler the practitioner is using to fill in the lips and frown lines. Botulinum toxin Wrinkle Cosmetic surgery In Pictures: Seven Of The Most Popular Injectable Facial Fillers How to Navigate the Anti–Ageing Maze And Not Get Lost PMMA Microspheres as Dermal Fillers

Princess Marie of Saxe-Weimar-Eisenach was a princess of Saxe-Weimar-Eisenach, by birth, and, by marriage, a princess of Prussia. She was the daughter of Charles Frederick, Grand Duke of Saxe-Weimar-Eisenach and Grand Duchess Maria Pavlovna of Russia. Princess Marie was the eldest daughter of Prince, Grand Duke, Charles Frederick of Saxe-Weimar-Eisenach and his wife, Grand Duchess Maria Pavlovna, the sister of Emperor Alexander I of Russia, her father was a shy man, whose favourite reading material were fairy tales until the end of his life. Her mother, by contrast, was "one of the most significant women of her time", according to Johann Wolfgang von Goethe. Marie and her younger sister Augusta, who became German Empress, received a comprehensive education, which focused on the courtly ceremonial duties they were to have as adults; this education included painting lessons by the court painter Louise Seidler and music lessons by the court conductor Johann Nepomuk Hummel. Marie grew up at the court in Weimar, considered one of the most liberal in Germany.

Saxe-Weimar-Eisenach adopted a constitution in 1816. The court was receptive towards literature and other art forms, due to the influence of the late Duchess Anna Amalia, who had died in 1807. Goethe had been managing the court theater in Weimar until 1817 and remained a welcome guest at the ducal court afterwards. Marie's grandfather, Duke Charles August was raised to Grand Duke in 1815, due to the influence of the Tsar and his own attitude at the Congress of Vienna; this allowed Marie to use the style Royal Highness. Saxe-Weimar-Eisenach achieved a considerable territorial expansion during the Congress of Vienna. Marie was 16 years old when she first met her future husband, Prince Charles of Prussia, in Frankfurt an der Oder in 1824, he was the third son of King Frederick William III of Louise of Mecklenburg-Strelitz. Grand Duchess Maria Pavlovna and her two daughters were travelling to Russia and had arranged to meet her brother, Grand Duke, Tsar and his wife Alexandra Feodorovna in Frankfurt.

When they arrived in Frankfurt, they were welcomed by Prince Charles and his brother William I. King Frederick William III was in favour of Charles marrying Marie and contacted the courts in Saint Petersburg and Weimar to negotiate a marriage arrangement. At the time, Maria Feodorovna, the mother of the Tsar, was still the authority in family matters. Neither she, nor Grand Duchess Maria Pavlovna, gave the response that Frederick William III had hoped for. Both courts were hoping that Marie could marry an heir to the throne, albeit a throne of a smaller country; the third son of a king was not quite. The Russians proposed that Marie could marry William and his younger brother Charles would marry her younger sister Augusta; this would be a better fit in terms of age and would satisfy the court in Weimar, William liked Marie more than he did Augusta. Frederick William III, saw nothing in this proposal, which ignored the feelings of his sons. Things were further complicated by William's being in love with Princess Elisa Radziwill.

Grand Duchess Maria Pavlovna tried to defame Ms. Radziwiłł with every means available. Outwardly, she did not want to base her daughter's marriage on the ruins of William's happiness, she hoped that William would marry Elisa morganatically, not have a legitimate heir, the Prussian throne would be inherited by the heirs of Charles and Marie. So she would not have been happy if William were to break off his relationship with Elisa and marry a lady of his own rank and have legitimate heirs. An ally in her quest to paint Elisa as lower nobility was Grand Duke George of Mecklenburg-Strelitz, brother of Charles and William's late mother Queen Louise. Negotiations had lasted more than two years when Maria Feodorovna managed to persuade her daughter to agree to a marriage between Charles and Marie, without putting any conditions on William. On 26 May 1827, Princess Marie married Prince Charles of Prussia in Charlottenburg, their son, Frederich Charles, was born 10 months later. Marie's sister Augusta and Charles' brother Wilhelm gave in to dynastic pressure and married two years later.

Their marriage, was complex and happy one. William regarded his wife as an "outstanding personality", but as less charming than her older sister. Augusta, on the other hand, was full of hope for a happy marriage, she was aware of his unrequited love of Elisa Radziwiłł. Charles and Marie had three children: Prince Frederick Charles of Prussia. Marie had lower status, being married to a mere Prince, she and her husband always resented their inferior position at court. While Charles took out his frustrations on womanizing and political schemes, Marie vied with Augusta over clothes and jewels. Charles and Marie ran a fashionable household, surrounding themselves with high society, unlike the sober Wilhelm and intellectual Augusta. Marie loathed both her successor Victoria, Princess Royal; as Victoria was British, most of the vehemently anti-British court was in agreement with Marie that it would have been bet