Talcahuano is a port city and commune in the Biobío Region of Chile. It is part of the Greater Concepción conurbation. Talcahuano is located in the south of the Central Zone of Chile.

Central Chile is one of the five natural regions into which CORFO divided continental Chile in 1950. It is home to a majority of the Chilean population and includes the three largest metropolitan areas—Santiago, Valparaíso, and Concepción. It extends from 32° south latitude to 37° south latitude.