Tanabe is a city located in Wakayama Prefecture, Japan. As of 1 November 2021, the city had an estimated population of 70,972 in 35076 households and a population density of 69 persons per km2. The total area of the city is 1,026.91 square kilometres (396.49 sq mi). Tanabe is the second largest city in Wakayama in terms of population, and the largest in the Kansai region of Japan in terms of area.