A tank gun is the main armament of a tank. Modern tank guns are high-velocity, large-caliber artilleries capable of firing kinetic energy penetrators, high-explosive anti-tank, and cannon-launched guided projectiles. Anti-aircraft guns can also be mounted to tanks.

A tank is an armoured fighting vehicle intended as a primary offensive weapon in front-line ground combat. Tank designs are a balance of heavy firepower, strong armour, and battlefield mobility provided by tracks and a powerful engine; their main armament is often mounted within a turret. They are a mainstay of modern 20th and 21st century ground forces and a key part of combined arms combat.