The San Sebastian Cathedral, also referred to as the Tarlac Cathedral, is a post-war, Neo-Gothic Roman Catholic church located in Brgy. Mabini, Tarlac City, Philippines. The cathedral, which was dedicated to Saint Sebastian in 1686, is the seat of the Roman Catholic Diocese of Tarlac. A historical marker of the National Historical Commission of the Philippines was unveiled near the cathedral's entrance on July 15, 2022.

Tarlac City, officially the City of Tarlac, is a 1st class component city and capital of the province of Tarlac, Philippines. According to the 2020 census, it has a population of 385,398 people.