Tecumseh's confederacy was a confederation of indigenous peoples in the Great Lakes region of North America that began to form in the early 19th century around the teaching of Tenskwatawa, called The Prophet by his followers. The confederation grew over several years and came to include several thousand warriors. Shawnee leader Tecumseh, the brother of The Prophet, developed into the leader of the group as early as 1808. Together, they worked to unite the various tribes against the European settlers who had been crossing the Appalachian Mountains and settling on their land.

A confederation is a political union of sovereign states united for purposes of common action. Usually created by a treaty, confederations of states tend to be established for dealing with critical issues, such as defence, foreign relations, internal trade or currency, with the central government being required to provide support for all its members. Confederalism represents a main form of intergovernmentalism, defined as any form of interaction around states that takes place on the basis of sovereign independence or government.