"Tell Me When to Go" is the first single from E-40's BME/Warner Bros. debut, My Ghetto Report Card. Keak da Sneak is also featured on the track. It was produced by Lil Jon, and one of the first singles to kick off the hyphy movement on a national level and popularized the phrase "ghost ride the whip". The song reached number 35 in the U.S. and eventually was certified Platinum by the RIAA on February 2, 2024. The song first premiered online on the MySpace.com homepage and it was the first hip hop single to premiere online before being released.

Earl Tywone Stevens Sr., better known by his stage name E-40, is an American rapper. He is a founding member of the rap group The Click and the founder of Sick Wid It Records. He has released 26 studio albums to date, appeared on numerous movie soundtracks, and has also done guest appearances on a host of other rap albums. Initially an underground artist, his 1995 solo album In a Major Way opened him up to a wider audience. Beginning in 1998, he began collaborating with mainstream rappers outside the San Francisco Bay Area. He rose to higher mainstream popularity in 2006 with his single "Tell Me When to Go", which was produced by Lil Jon.