The ten principal disciples were the main disciples of Gautama Buddha. Depending on the scripture, the disciples included in this group vary. In many Mahāyāna discourses, these ten disciples are mentioned, but in differing order. The ten disciples can be found as an iconographic group in notable places in the Mogao Caves. They are mentioned in Chinese texts from the fourth century BCE until the twelfth century CE, and are the most honored of the groups of disciples, especially so in China and Central Asia. The ten disciples are mentioned in the Mahāyāna text Vimalakīrti-nideśa, among others. In this text, they are called the "Ten Wise Ones", a term which is normally used for the disciples of Confucius.

Maudgalyāyana, also known as Mahāmaudgalyāyana or by his birth name Kolita, was one of the Buddha's closest disciples. Described as a contemporary of disciples such as Subhuti, Śāriputra, and Mahākāśyapa, he is considered the second of the Buddha's two foremost male disciples, together with Śāriputra. Traditional accounts relate that Maudgalyāyana and Śāriputra become spiritual wanderers in their youth. After having searched for spiritual truth for a while, they come into contact with the Buddhist teaching through verses that have become widely known in the Buddhist world. Eventually they meet the Buddha himself and ordain as monks under him. Maudgalyāyana attains enlightenment shortly after that.