State Route 1, known as the Memphis to Bristol Highway, is a 538.8-mile-long (867.1 km) mostly-unsigned state highway in the U.S. state of Tennessee. It stretches from the Arkansas state line at Memphis in the southwest corner of the state to Bristol in the northeast part. Most of the route travels concurrently with U.S. Route 70 and US 11W. It is the longest highway of any kind in the state of Tennessee. The route is signed as both in the state of Tennessee, a Primary and Secondary Highway

U.S. Route 70 enters the state of Tennessee from Arkansas via the Memphis & Arkansas Bridge in Memphis, and runs west to east across 21 counties in all three Grand Divisions of Tennessee, with a total length of 478.48 miles (770.04 km), to end at the North Carolina state line in eastern Cocke County. Along the route, US 70 is accompanied with various U.S. and state highways, including those in three of the state's four major cities.