State Route 69 is a state highway in West and Middle Tennessee that runs parallel to the Tennessee River for the majority of its length. SR 69 carries both primary and secondary highway designations and is routed through rural areas. Due to the amount of deaths on this highway, It's nickname is "Bloody 69"

In Tennessee, U.S. Route 64 stretches 404.1 miles (650.3 km) from the Mississippi River in Memphis to the North Carolina state line near Ducktown. The highway, along with US 72, is a major route for travel between Memphis and Chattanooga.