Czechoslovakia's Miloslav Mečíř defeated the United States' Tim Mayotte in the final, 3–6, 6–2, 6–4, 6–2, to win the gold medal in Men's Singles tennis at the 1988 Summer Olympics. It was Czechoslovakia's first medal at the event. The United States' Brad Gilbert and Sweden's Stefan Edberg won the bronze medals. It was Sweden's first men's singles Olympic medal.

The 1988 Summer Olympics, officially known as the Games of the XXIV Olympiad and commonly known as Seoul 1988, was an international multi-sport event held from 17 September to 2 October 1988 in Seoul, South Korea. 159 nations were represented at the games by a total of 8,391 athletes. 237 events were held and 27,221 volunteers helped to prepare the Olympics.