The Tenshō embassy was an embassy sent by the Japanese Christian Lord Ōtomo Sōrin to the Pope and the kings of Europe in 1582. The embassy was led by Mancio Itō, a Japanese nobleman, who was the first official Japanese emissary to Europe.

Ōtomo Sōrin , also known as Fujiwara no Yoshishige or Ōtomo Yoshishige, was a Japanese feudal lord (daimyō) of the Ōtomo clan, one of the few to have converted to Roman Catholicism (Christianity). The eldest son of Ōtomo Yoshiaki, he inherited the Funai Domain, on Kyūshū, Japan's southernmost main island, from his father. He is perhaps most significant for having appealed to Toyotomi Hideyoshi to intervene in Kyūshū against the Shimazu clan, thus spurring Hideyoshi's Kyūshū Campaign of 1587.