Tequixquiac is a municipality located in the Zumpango Region of the State of Mexico in Mexico. The municipality is located 84 kilometres (52 mi) north of Mexico City within the valley that connects the Valley of Mexico with the Mezquital Valley. The name comes from Nahuatl and means "place of tequesquite waters". The municipal seat is the town of Santiago Tequixquiac, although both the town and municipality are commonly referred to as simply "Tequixquiac".

The State of Mexico, officially just Mexico, is one of the 32 federal entities of the United Mexican States. Commonly known as Edomex to distinguish it from the name of the whole country, it is the most populous, as well as the most densely populated, state in the country.