The Terre Haute, Indianapolis and Eastern Traction Company, or THI&E, was the second largest interurban in the U.S. state of Indiana during the height of the 1920s "interurban era." This system included over 400 miles (640 km) of track, with lines radiating from Indianapolis to the east, northwest, west and southwest as well as streetcar lines in several major cities. The THI&E was formed in 1907 by the Schoepf-McGowan Syndicate as a combination of several predecessor interurban and street car companies and was operated independently until incorporation into the Indiana Railroad in 1931. The THI&E served a wide range of territory, including farmlands in central Indiana, the mining region around Brazil, and numerous urban centers. Eventually, it slowly succumbed like all of the other central Indiana interurban lines, to competition from automobiles, trucks, and improved paralleling highways.

The Indiana Railroad (IR) was the last of the typical Midwestern United States interurban lines. It was formed in 1930–31 by combining the operations of the five major interurban systems in central Indiana into one entity. The predecessor companies came under the control of Midland Utilities, owned by Samuel Insull. His plan was to modernize the profitable routes and abandon the unprofitable ones. With the onset of the Great Depression, the Insull empire collapsed and the Indiana Railroad was left with a decaying infrastructure and little hope of overcoming the growing competition of the automobile for passenger business and the truck for freight business. The IR faced bankruptcy in 1933, and Bowman Elder was designated as the receiver to run the company. Payments on bonded debt were suspended. Elder was able to keep the system virtually intact for four years, and IR operated about 600 miles (970 km) of interurban lines throughout Indiana during this period. During the late 1930s, the routes were abandoned one by one until a 1941 wreck with fatalities south of Indianapolis put an abrupt end to the Indiana Railroad's last passenger operations.