The Texas Mexican Railway International Bridge is an international railway bridge across the Rio Grande and U.S.-Mexico border between Laredo, Texas, and Nuevo Laredo, Tamaulipas, the only rail link between these cities. Owned and operated by CPKC, the single-track bridge is the busiest rail border crossing in North America. It is also known as the Laredo International Railway Bridge and Puente Negro.

Nuevo Laredo is a city in the Municipality of Nuevo Laredo in the Mexican state of Tamaulipas. The city lies on the banks of the Rio Grande, across from Laredo, United States. The 2010 census population of the city was 373,725. Nuevo Laredo is part of the Laredo-Nuevo Laredo Metropolitan Area with a population of 636,516. The municipality has an area of 1,334.02 km2 (515.07 sq mi). Nuevo Laredo is considered the “customs capital of Latin America” because of its high volume of international trade operations in the region, and number 1 in importance for US inland commercial traffic. Both the city and the municipality rank as the third largest in the state.