State Highway 16 is a south–north state highway in the U.S. state of Texas that runs from Zapata on the boundary with Mexico to U.S. Highway 281 24 miles (39 km) south of Wichita Falls. It is the longest state highway in Texas at almost 542 miles (872 km), but is only the ninth-longest of any highway classification in the state.

U.S. Highway 83 (US 83), dedicated as the Texas Vietnam Veterans Memorial Highway, is a U.S. Highway in the U.S. state of Texas that begins at US 77 in Brownsville and follows the Rio Grande to Laredo, then heads north through Abilene to the Oklahoma state line north of Perryton, the seat of Ochiltree County.