Texas Woman's University (TWU) is a public coeducational university in Denton, Texas, with two health science center-focused campuses in Dallas and Houston. While TWU has been fully co-educational since 1994, it is the largest state-supported university primarily for women in the United States. The university is part of the Texas Woman's University System. It offers undergraduate and graduate degree programs in 60 areas of study across six colleges.

Denton is a city in the U.S. state of Texas and the seat of Denton County. With a population of 139,869 as of 2020, it is the 20th-most populous city in Texas, the 177th-most populous city in the United States, and the 12th-most populous city in the Dallas–Fort Worth metroplex.