Thado Dhamma Yaza I was viceroy of Prome (Pyay) from 1542 to 1550 during the reign of his son-in-law King Tabinshwehti of Toungoo Dynasty of Burma (Myanmar), and the self-proclaimed king of the city-state from 1550 to 1551. After the death of Tabinshwehti in 1550, the man who started out as a royal household servant of Tabinshwehti in 1516 declared himself king of Prome with the style of Thado Thu, and did not submit to Bayinnaung, Tabinshwehti's chosen successor. His fortified city-state fell to Bayinnaung's forces in 1551 after a six-month battle. He was executed on the order of Bayinnaung, who later regretted the decision.

Tabinshwehti was king of Burma (Myanmar) from 1530 to 1550, and the founder of the First Toungoo Empire. His military campaigns (1534–1549) created the largest kingdom in Burma since the fall of the Pagan Empire in 1287. His administratively fragile kingdom proved to be the impetus for the eventual reunification of the entire country by his successor and brother-in-law Bayinnaung.