Thampanoor is the geographic center (CBD) of the Indian city of Thiruvananthapuram. The busiest railway station of the state in terms of daily passengers, Thiruvananthapuram Central, is located at Thampanoor. It caters an average of 40,908 passengers a day (2017–2018), making it as the busiest railway station in Kerala. Opposite to the railway station is the major Bus Terminal of Kerala, the Central Bus Station, Thiruvananthapuram (TVM) which is the largest and the busiest Bus station in the state connecting to almost all the parts of the State and other interstate cities. Thampanoor is administered by Thiruvananthapuram Corporation. Councillor of Thampanoor Corporation Ward is Harikumar. It falls under the Thiruvananthapuram which inturn comes under one of the seven assemblies under the Thiruvananthapuram.

Thiruvananthapuram Central (station code: TVC) is an NSG–2 category Indian railway station in Thiruvananthapuram railway division of Southern Railway zone. It is a major railway station that serves the city of Thiruvananthapuram, the capital of Kerala. It is Kerala's busiest railway station and a Southern Railway zone. The station, a Thiruvananthapuram landmark, is in the center of the city (Thampanoor) opposite the central bus station.