The Centennial, formerly The 925 Building, and Huntington Building, originally the Union Trust Building, is a high-rise office building on Euclid Avenue in the Nine-Twelve District of downtown Cleveland, Ohio, USA. When the building was completed in 1924, it was the second largest building in the world in terms of floor space, with more than 30 acres of floor space. It also included the world's largest bank lobby, which today remains among the largest in the world. The lobby features enormous marble Corinthian columns, barrel vaulted ceilings, and colorful murals by Jules Guerin.

Euclid Avenue is a major street in Cleveland, Ohio, United States. It runs northeasterly from Public Square in Downtown Cleveland, passing Playhouse Square and Cleveland State University, to University Circle, the Cleveland Clinic, Severance Hall, Case Western Reserve University's Maltz Performing Arts Center, Case Western Reserve University and University Hospitals Case Medical Center. The street runs through the suburbs of East Cleveland, Euclid, and Wickliffe, to Willoughby as a part of U.S. Route 20 and U.S. Route 6. The HealthLine bus rapid transit line runs in designated bus lanes in the median of Euclid Avenue from Public Square to Louis Stokes Station at Windermere in East Cleveland.