The Amber Ruffin Show is an American comedy late-night talk show. Produced by Universal Television and Sethmaker Shoemeyers Productions and starring Amber Ruffin, it features a mix of sketches and monologues. The series was ordered for nine half-hour episodes and premiered on NBCUniversal's video-streaming service Peacock on September 25, 2020. Peacock ordered an additional 10 episodes in December 2020, and the series was promoted with a brief run on the NBC broadcast network in February and March 2021. The third season premiered on September 30, 2022. In 2023, it was announced the program would only return on occasion as specials but these were never ordered.

Amber Mildred Ruffin is an American comedian, writer and actress. She hosted her own late-night talk show titled The Amber Ruffin Show on Peacock. She has been a writer for Late Night with Seth Meyers since 2014. When she joined the show she became the first Black woman to write for a late-night network talk show in the United States.