The Business of Strangers is a 2001 American drama film that tells the story of an eventful night shared between a middle-aged businesswoman and her young assistant. The independent film was written and directed by Patrick Stettner. It stars Stockard Channing and Julia Stiles.

Stockard Channing is an American actress. She played Betty Rizzo in the film Grease (1978) and First Lady Abbey Bartlet in the NBC television series The West Wing (1999–2006). She also originated the role of Ouisa Kittredge in the stage and film versions of Six Degrees of Separation; the 1993 film version earned her an Academy Award nomination for Best Actress. She was also one of two comic foils of The Number Painter on Sesame Street.